Every claim, graded.

The complete Realised knowledge base. Each entry shows its confidence tier, the reasoning behind it, the underlying sources, and (where relevant) what would change our mind.

entries · 6 pillars · last updated 2026

Methodology

Foundational

Physiological axioms or replicated baseline-recovery protocols. Not in scientific dispute. Includes Tier 0 axioms and Tier 0.5 foundational synthesis.

Strong

Multiple independent replications, well-understood mechanism, meta-analytic support. Tier 1.

Moderate

Replicated but with caveats: smaller effects, partial mechanism, or evidence concentrated in specific populations. Tier 2.

Emerging

Early-stage support, single high-quality studies, or pre-replication signals with strong mechanism. Tier 3.

Experimental

Preliminary, contested, or theoretical. Included for transparency. Tier 4.

How tiers get assigned

Tier reflects how confident Realised is in a claim, not just the type of study behind it. A meta-analysis with conflicting findings can sit at Moderate. A small RCT with a clean mechanism and replicated direction can sit at Strong. Each entry shows its tier reasoning: what evidence moved it up, what caveats hold it back, and where industry or publication bias may distort the picture.

Many entries have mixed tiers across dimensions. Vitamin D might be Strong for the underlying physiology, Moderate for clinical depression effect, and Emerging for respiratory infection prevention. We surface that split rather than flatten it.

Genetic claims: same discipline

Your genome is too important for "emerging research" framed as established fact.

The same tier system applies to genetic recommendations. Tier 1 for a genetic claim requires genotype-stratified intervention RCTs, replicated. Mechanism plus a non-stratified trial = Tier 2 at best. Most consumer genetics products grade at Tier 3 or Tier 4 by our standard. Most don't grade at all.

Realised does not publish claims at Experimental tier as recommendations. They appear here for transparency: so you can see where our knowledge base ends, not where the platform suggests you should act.

215 entries