CoQ10: A Few Real Niches, Not the Anti-Aging Energy Booster

Summary

CoQ10 is sold as a "cellular energy and anti-aging" tonic for everyone, and that pitch is unsupported — healthy people make enough of their own, there is no energy or longevity benefit in people who are not deficient, oral absorption is only a few percent without dietary fat, and even its flagship consumer use (statin muscle pain) has genuinely conflicting trials — yet the supplement is not a nothing: it has a handful of real, narrow niches where the evidence holds up (a mortality signal in chronic heart failure from the Q-SYMBIO trial, obligatory replacement in primary CoQ10 deficiency and mi